All the information in that article remains true – I have been taking CoQ10 supplements for years on the back of it.
Recently, however, I switched from CoQ10 (ubiquinone) supplements to CoQH (ubiquinol) – the bio available form of CoQ10 after reading and seeing the results of some recent research studies.
I can almost hear the groans – just as we all get our heads around what CoQ10 is – the science moves on but don’t worry this is very good news.
Ubiquinol vs Ubiquinone?
In simple terms ubiquinol is the converted or bio-available form of ubiquinone (CoQ10).
In younger adults CoQ10 (ubiquinone) is converted by the body into ubiquinol – a form that can be absorbed into the bloodstream. Taking ubiquinol supplements allows your body to skip the step of conversion and start using this amazing substance immediately.
This may sound like a fine bit of scientific hair splitting – but it isn’t. Since it has already been converted, ubiquinol is absorbed by the body up to eight times better than simple CoQ10 and stays in the blood for far longer.
Essentially ubiquinol is the “bio-identical” form of CoQ10 that the body can utilise, store and process most efficiently. It’s a distinction that matters a lot the older you get since we lose the ability to convert CoQ10 into ubiquinol with advancing age.
The reality is no matter how much ubiquinone CoQ10 you take past late middle age and into your senior years – your body simply won’t be able to covert it efficiently or at all.
For us oldies – as we get older – the only way to get the anti aging and health benefits of CoQ10 is to take it in its already converted form – as ubiquinol.
You may wonder why we didn’t know this before – why was I urging you to take simple CoQ10 (ubiquinone) supplements in my earlier article?
The fact is that ubiquinol has only recently been developed in supplement form (since 2006) and the real benefits are still emerging as more and more studies are completed.
Ubiquinol shown to slow aging
One key finding from recent research – ubiquinol has been shown to radically slow the aging process.
In an important Japanese study from the company that developed ubiquinol in supplement form – Kineka – scientists studied its effect on mice. Not just ordinary mice either but “senescence-accelerated” mice. Simply put these are mice specially developed to grow normally but age at an accelerated rate.
A grading score was developed to assess the aging process – based on things like: reduced physical activity, coarser skin, hair loss, occular lesions and curvature of the spine. The higher the score the more advanced the aging process.
Mice fed standard CoQ10 were compared to mice fed ubiquinol as well as to a control group on a normal diet without any supplements.
As the research progressed and the mice entered “middle age” – differences in the rate of aging became very noticeable and then accelerated even more.
At the equivalent of “late middle age” mice receiving ubiquinol had a 51% slower rate of aging than those on a normal diet and 40% less signs of aging than mice given ordinary CoQ10.
At 12 months – “old age” in terms of the study – results were so staggering that the scientists started to take photographs of the mice in different groups which were eventually published as part of the research results.
The elderly mice in the ubiquinol group appear perfectly bright and healthy. In comparison – the ubiquinone (standard CoQ10) group have suffered noticeable degenerative changes and unsurprisingly the control group look horrendous.
Videos of the mice taken at this 12 month point show that the elderly mice given ubiquinol appear to be healthy, mobile, glossy-coated and alert – compared to the other two groups who look immobile, unresponsive and clearly suffering from advanced aging.
The video is available on YouTube and my instant reaction was to ditch my ubiquinone CoQ10 supplements and start taking ubiquinol CoQH.
Not surprisingly similar studies followed. In one – scientists took three groups of rats and measured how long they could run on a treadmill. Results showed that while ordinary CoQ10 supplements boosted running time (stamina) by 60% – rats given ubiquinol lasted an incredible 150% longer on the treadmill compared to the control group on a normal diet.
When should you start taking ubiquinol?
You might think that everyone should start taking this amazing supplement immediately but that would be overkill.
The reality is that under 40 you should be able to rely on standard CoQ10 (ubiquinone) supplements. The reason is simple – in your twenties and thirties your body is still able to convert CoQ10 to ubiquinol in the bloodstream. CoQ10 (ubiquinone) supplements will be enough to give you the anti aging and health advantages you want.
After 40 things change for the worse. Our ability to convert natural CoQ10 into ubiquinol rapidly deteriorates – contributing to some of the worst aspects of aging and age related decline. You need to get your CoQ10 in a bio-available form already converted to ubiquinol for immediate use.
From around the age of 40 onwards – if you haven’t already done so – switch from ubiquinone CoQ10 to ubiquinol CoQH supplements.
How much ubiquinol should you take?
As with all supplements it is crucial to buy from a reputable source.
All ubiquinol is still produced by Kaneka – trade-marked “KanekaQH” and sold – not to the general public – but only to reputable supplement producers. Whoever you buy from – you need to make sure your ubiquinol is from this Kaneka source.
In terms of dosage the advice is for people with generally low levels of CoQ10 to start with an initial high booster dose of 200-300 mgs daily. Split the dose into two so you maintain high levels of CoQ10 in the bloodstream over the whole day and continue for two weeks when you can drop to around 100-150 mgs per day to.
This is probably a minimum recommended level – maintaining a higher dose is unlikely to do any harm and may well bring added anti aging and health effects. If it helps – I started off on 300 mgs for the first two weeks and then dropped to a daily 150 mgs.
I’m not sure how I would compare with a bright and bushy tailed, alert, senior mouse – but I certainly feel great!